What is Carpal Tunnel? Carpal Tunnel can occur when the median nerve is compressed. The median nerve is located on the palm side of your hand. This nerve provides sensation to the hand. When affected blood circulation to fingers gets cut off Carpal Tunnel may occur. It an be in one or both of your hands. Carpal Tunnel can occur when the median nerve is compressed. Logically speaking the passageway is hindered, which is why numbness is one of the effects of carpal tunnel syndr